| 1 | Camilo Sanvezzo
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 31 | 22 |
| 2 | Mike Magee
Chicago Fire FC | Chicago Fire FC | 22 | 21 |
| 3 | Marco Di Vaio
CF Montréal | CF Montréal | 34 | 20 |
| 4 | Robbie Keane
LA Galaxy | LA Galaxy | 25 | 16 |
| 5 | Álvaro Saborío
Real Salt Lake | Real Salt Lake | 19 | 13 |
| - | Diego Fagundez
New England Revolution | New England Revolution | 33 | 13 |
| - | Dominic Oduro
Columbus Crew SC | Columbus Crew SC | 34 | 13 |
| - | Will Johnson
Portland Timbers | Portland Timbers | 32 | 13 |
| 9 | Claudio Bieler
Sporting Kansas City | Sporting Kansas City | 31 | 12 |
| - | Jack Mclnerney
Philadelphia Union | Philadelphia Union | 31 | 12 |
| - | Tim Cahill
New York Red Bulls | New York Red Bulls | 29 | 12 |
| 12 | Eddie Johnson
Seattle Sounders FC | Seattle Sounders FC | 24 | 11 |
| - | Blas Pérez
FC Dallas | FC Dallas | 25 | 11 |
| - | Conor Casey
Philadelphia Union | Philadelphia Union | 31 | 11 |
| - | Diego Valeri
Portland Timbers | Portland Timbers | 35 | 11 |
| - | Federico Higuaín
Columbus Crew SC | Columbus Crew SC | 29 | 11 |
| - | Chris Wondolowski
San Jose Earthquakes | San Jose Earthquakes | 29 | 11 |
| 18 | Landon Donovan
LA Galaxy | LA Galaxy | 24 | 10 |
| - | Deshorn Brown
Colorado Rapids | Colorado Rapids | 32 | 10 |
| - | Thierry Henry
New York Red Bulls | New York Red Bulls | 32 | 10 |
| - | Javier Morales
Real Salt Lake | Real Salt Lake | 33 | 10 |
| - | Will Bruin
Houston Dynamo FC | Houston Dynamo FC | 34 | 10 |
| - | Darlington Nagbe
Portland Timbers | Portland Timbers | 38 | 10 |
| 24 | Edgar Espíndola
New York Red Bulls | New York Red Bulls | 29 | 9 |
| - | Giles Barnes
Houston Dynamo FC | Houston Dynamo FC | 38 | 9 |
| 26 | Obafemi Martins
Seattle Sounders FC | Seattle Sounders FC | 21 | 8 |
| - | Robbie Findley
Real Salt Lake | Real Salt Lake | 30 | 8 |
| - | Kenny Miller
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 21 | 8 |
| - | Rob Earnshaw
Toronto FC | Toronto FC | 26 | 8 |
| - | Lamar Neagle
Seattle Sounders FC | Seattle Sounders FC | 32 | 8 |
| - | Kelyn Rowe
New England Revolution | New England Revolution | 35 | 8 |
| 32 | Kei Kamara
Sporting Kansas City | Sporting Kansas City | 15 | 7 |
| - | Erick Torres
Chivas USA | Chivas USA | 15 | 7 |
| - | Juan Agudelo
New England Revolution | New England Revolution | 16 | 7 |
| - | Rodney Wallace
Portland Timbers | Portland Timbers | 31 | 7 |
| - | Aurelien Collin
Sporting Kansas City | Sporting Kansas City | 34 | 7 |
| 37 | Kekuta Manneh
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 20 | 6 |
| - | Kenny Cooper
FC Dallas | FC Dallas | 31 | 6 |
| - | C.J. Sapong
Sporting Kansas City | Sporting Kansas City | 30 | 6 |
| - | Graham Zusi
Sporting Kansas City | Sporting Kansas City | 32 | 6 |
| 41 | Lloyd Sam
New York Red Bulls | New York Red Bulls | 24 | 5 |
| - | Olmes García
Real Salt Lake | Real Salt Lake | 26 | 5 |
| - | Saer Sene
New England Revolution | New England Revolution | 24 | 5 |
| - | Joao Plata
Real Salt Lake | Real Salt Lake | 31 | 5 |
| - | Jonathan Osorio
Toronto FC | Toronto FC | 28 | 5 |
| - | Brad Evans
Seattle Sounders FC | Seattle Sounders FC | 27 | 5 |
| - | Atiba Harris
Colorado Rapids | Colorado Rapids | 30 | 5 |
| - | Boniek García
Houston Dynamo FC | Houston Dynamo FC | 27 | 5 |
| - | Felipe
CF Montréal | CF Montréal | 33 | 5 |
| - | Dillon Powers
Colorado Rapids | Colorado Rapids | 30 | 5 |